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Dinitroanilines Bind α-Tubulin to Disrupt Microtubules

Protozoan parasites are remarkably sensitive to dinitroanilines such as oryzalin, which disrupt plant but not animal microtubules. To explore the basis of dinitroaniline action, we isolated 49 independent resistant Toxoplasma gondii lines after chemical mutagenesis. All 23 of the lines that we exami...

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Autors principals: Morrissette, Naomi S., Mitra, Arpita, Sept, David, Sibley, L. David
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC379290/
https://ncbi.nlm.nih.gov/pubmed/14742718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-07-0530
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