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Identification of a Novel Microtubule-destabilizing Motif in CPAP That Binds to Tubulin Heterodimers and Inhibits Microtubule Assembly

We have previously identified a new centrosomal protein, centrosomal protein 4.1-associated protein (CPAP), which is associated with the γ-tubulin complex. Here, we report that CPAP carries a novel microtubule-destabilizing motif that not only inhibits microtubule nucleation from the centrosome but...

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Detalhes bibliográficos
Main Authors: Hung, Liang-Yi, Chen, Hua-Ling, Chang, Ching-Wen, Li, Bor-Ran, Tang, Tang K.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC420094/
https://ncbi.nlm.nih.gov/pubmed/15047868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-02-0121
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