Targeting human CD34(+) hematopoietic stem cells with anti-CD45 × anti-myosin light-chain bispecific antibody preserves cardiac function in myocardial infarction

We have previously shown that targeting human CD34(+) hematopoietic stem cells (HSC) with a bispecific antibody (BiAb) directed against myosin light chain (MLC) increases delivery of cells to the injured hearts and improves cardiac performance in the nude rat. In this study, we have sought to valida...

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Hauptverfasser: Zhao, Ting C., Tseng, Andy, Yano, Naohiro, Tseng, YiTang, Davol, Pamela A., Lee, Randall J., Lum, Lawrence G., Padbury, James F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792713/
https://ncbi.nlm.nih.gov/pubmed/18292296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.01109.2007
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