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Targeting Cytomegalovirus-Infected Cells Using T Cells Armed with Anti-CD3 × Anti-CMV Bispecific Antibody

Human cytomegalovirus (CMV) reactivation and infection can lead to poor outcomes after allogeneic stem cell transplantation. We hypothesized that anti-CD3 activated T cells (ATCs) armed with chemically heteroconjugated anti-CD3 × polyclonal anti-CMV bispecific antibody (CMVBi) will target and elimin...

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Detalhes bibliográficos
Main Authors: Lum, Lawrence G., Ramesh, Mayur, Thakur, Archana, Mitra, Subhashis, Deol, Abhinav, Uberti, Joseph P., Pellett, Philip E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792653/
https://ncbi.nlm.nih.gov/pubmed/22313635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2012.01.022
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