A Prader–Willi locus lncRNA cloud modulates diurnal genes and energy expenditure

Prader–Willi syndrome (PWS), a genetic disorder of obesity, intellectual disability and sleep abnormalities, is caused by loss of non-coding RNAs on paternal chromosome 15q11-q13. The imprinted minimal PWS locus encompasses a long non-coding RNA (lncRNA) transcript processed into multiple SNORD116 s...

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Main Authors: Powell, Weston T., Coulson, Rochelle L., Crary, Florence K., Wong, Spencer S., Ach, Robert A., Tsang, Peter, Alice Yamada, N., Yasui, Dag H., LaSalle, Janine M.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792690/
https://ncbi.nlm.nih.gov/pubmed/23771028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt281
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