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LRP6 exerts non-canonical effects on Wnt signaling during neural tube closure

Low-density lipoprotein receptor related protein 6 (Lrp6) mutational effects on neurulation were examined using gain (Crooked tail, Lrp6(Cd)) and loss (Lrp6(−)) of function mouse lines. Two features often associated with canonical Wnt signaling, dorsal–ventral patterning and proliferation, were no d...

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Detalhes bibliográficos
Main Authors: Gray, Jason D., Kholmanskikh, Stanislav, Castaldo, Bozena S., Hansler, Alex, Chung, Heekyung, Klotz, Brian, Singh, Shawn, Brown, Anthony M. C., Ross, M. Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792688/
https://ncbi.nlm.nih.gov/pubmed/23773994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt277
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