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Untargeted Metabolite Profiling of Murine Embryos to Reveal Metabolic Perturbations Associated with Neural Tube Closure Defects
BACKGROUND: Neural tube closure defects (NTDs) are among the most common congenital malformation in human, typically presenting in liveborns as spina bifida. At least 240 gene mutations in mouse are known to increase the risk of NTD. There is a growing appreciation that environmental factors signifi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4146720/ https://ncbi.nlm.nih.gov/pubmed/25115437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdra.23272 |
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