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Untargeted Metabolite Profiling Reveals that Nitric Oxide Bioynthesis is an Endogenous Modulator of Carotenoid Biosynthesis in Deinococcus radiodurans and is Required for Extreme Ionizing Radiation Resistance

Deinococcus radiodurans (Drad) is the most radioresistant organism known. Although mechanisms that underlie the extreme radioresistance of Drad are incompletely defined, resistance to UV irradiation-induced killing was found to be greatly attenuated in an NO synthase (NOS) knockout strain of Drad (Δ...

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Detalhes bibliográficos
Publicado no:Arch Biochem Biophys
Main Authors: Hansler, Alex, Chen, Qiuying, Ma, Yuliang, Gross, Steven S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698065/
https://ncbi.nlm.nih.gov/pubmed/26550929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2015.10.010
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