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Expression, purification and crystallization of the FP domain of the human F-box protein Fbxo7

Fbxo7 is a conserved protein in higher eukaryotes that belongs to the F-box protein family. Fbxo7 is the substrate-recognition component of the SCF(Fbxo7) (Skp1-Cul1-Fbox protein) E3 ubiquitin ligase. Besides the F-box motif, Fbxo7 also contains a C-terminal proline-rich region, an N-terminal ubiqui...

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Détails bibliographiques
Auteurs principaux: Shang, Jinsai, Wang, Guan, Yang, Yang, Huang, Xiaolan, Du, Zhihua
Format: Artigo
Langue:Inglês
Publié: International Union of Crystallography 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792664/
https://ncbi.nlm.nih.gov/pubmed/24100556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309113023154
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