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INTROGRESSION OF BROWN NORWAY CYP4A GENES ONTO THE DAHL SALT-SENSITIVE BACKGROUND RESTORES VASCULAR FUNCTION IN SS-5(BN) CONSOMIC RATS
This study tested the hypothesis that the Dahl salt-sensitive (SS) rat has vascular dysfunction due, in part, to the upregulation of the cytochrome P450-4A ω-hydroxylase (CYP4A)/20-hydroxyeicosatetraenoic acid (20-HETE) system. To assess the role of vascular 20-HETE, SS were compared to SS-5(BN) con...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3791890/ https://ncbi.nlm.nih.gov/pubmed/22938512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20120232 |
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