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Endothelin-2 signaling in the neural retina promotes the endothelial tip cell state and inhibits angiogenesis

Endothelin signaling is required for neural crest migration and homeostatic regulation of blood pressure. Here, we report that constitutive overexpression of Endothelin-2 (Edn2) in the mouse retina perturbs vascular development by inhibiting endothelial cell migration across the retinal surface and...

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書誌詳細
主要な著者: Rattner, Amir, Yu, Huimin, Williams, John, Smallwood, Philip M., Nathans, Jeremy
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791783/
https://ncbi.nlm.nih.gov/pubmed/24043815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1315509110
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