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Endothelin-2 signaling in the neural retina promotes the endothelial tip cell state and inhibits angiogenesis
Endothelin signaling is required for neural crest migration and homeostatic regulation of blood pressure. Here, we report that constitutive overexpression of Endothelin-2 (Edn2) in the mouse retina perturbs vascular development by inhibiting endothelial cell migration across the retinal surface and...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3791783/ https://ncbi.nlm.nih.gov/pubmed/24043815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1315509110 |
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