Mice lacking ANGPTL8 (Betatrophin) manifest disrupted triglyceride metabolism without impaired glucose homeostasis

Angiopoietin-like protein (ANGPTL)8 (alternatively called TD26, RIFL, Lipasin, and Betatrophin) is a newly recognized ANGPTL family member that has been implicated in both triglyceride (TG) and glucose metabolism. Hepatic overexpression of ANGPTL8 causes hypertriglyceridemia and increased insulin se...

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Главные авторы: Wang, Yan, Quagliarini, Fabiana, Gusarova, Viktoria, Gromada, Jesper, Valenzuela, David M., Cohen, Jonathan C., Hobbs, Helen H.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2013
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791734/
https://ncbi.nlm.nih.gov/pubmed/24043787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1315292110
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