Llwytho...

Tumor suppressor p16(INK4A) is necessary for survival of cervical carcinoma cell lines

The tumor suppressor p16(INK4A) inhibits formation of enzymatically active complexes of cyclin-dependent kinases 4 and 6 (CDK4/6) with D-type cyclins. Oncogenic stress induces p16(INK4A) expression, which in turn triggers cellular senescence through activation of the retinoblastoma tumor suppressor....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: McLaughlin-Drubin, Margaret E., Park, Donglim, Munger, Karl
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791710/
https://ncbi.nlm.nih.gov/pubmed/24046371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310432110
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