Učitavanje...
Tumor suppressor p16(INK4A) is necessary for survival of cervical carcinoma cell lines
The tumor suppressor p16(INK4A) inhibits formation of enzymatically active complexes of cyclin-dependent kinases 4 and 6 (CDK4/6) with D-type cyclins. Oncogenic stress induces p16(INK4A) expression, which in turn triggers cellular senescence through activation of the retinoblastoma tumor suppressor....
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| Glavni autori: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3791710/ https://ncbi.nlm.nih.gov/pubmed/24046371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310432110 |
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