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Discrimination of RNA versus DNA by polynucleotide phosphorylase

Polynucleotide phosphorylase (PNPase) plays synthetic and degradative roles in bacterial RNA metabolism; it is also suggested to participate in bacterial DNA transactions. Here we used chimeric polynucleotides, composed of alternating RNA and DNA tracts, to analyze whether and how Mycobacterium smeg...

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Detalhes bibliográficos
Main Authors: Unciuleac, Mihaela-Carmen, Shuman, Stewart
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791318/
https://ncbi.nlm.nih.gov/pubmed/23980617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi401041v
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