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Mapping the Interactions between the Alzheimer’s Aβ-Peptide and Human Serum Albumin beyond Domain Resolution

Human serum albumin (HSA) is a potent inhibitor of Aβ self-association and this novel, to our knowledge, function of HSA is of potential therapeutic interest for the treatment of Alzheimer’s disease. It is known that HSA interacts with Aβ oligomers through binding sites evenly partitioned across the...

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Autors principals: Algamal, Moustafa, Milojevic, Julijana, Jafari, Naeimeh, Zhang, William, Melacini, Giuseppe
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791307/
https://ncbi.nlm.nih.gov/pubmed/24094411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.08.025
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