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Mapping the Interactions between the Alzheimer’s Aβ-Peptide and Human Serum Albumin beyond Domain Resolution

Human serum albumin (HSA) is a potent inhibitor of Aβ self-association and this novel, to our knowledge, function of HSA is of potential therapeutic interest for the treatment of Alzheimer’s disease. It is known that HSA interacts with Aβ oligomers through binding sites evenly partitioned across the...

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Main Authors: Algamal, Moustafa, Milojevic, Julijana, Jafari, Naeimeh, Zhang, William, Melacini, Giuseppe
格式: Artigo
語言:Inglês
出版: The Biophysical Society 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791307/
https://ncbi.nlm.nih.gov/pubmed/24094411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.08.025
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