Age at Onset in Two Common Neurodegenerative Diseases Is Genetically Controlled

To identify genes influencing age at onset (AAO) in two common neurodegenerative diseases, a genomic screen was performed for AAO in families with Alzheimer disease (AD; n=449) and Parkinson disease (PD; n=174). Heritabilities between 40%–60% were found in both the AD and PD data sets. For PD, signi...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Li, Yi-Ju, Scott, William K., Hedges, Dale J., Zhang, Fengyu, Gaskell, P. Craig, Nance, Martha A., Watts, Ray L., Hubble, Jean P., Koller, William C., Pahwa, Rajesh, Stern, Matthew B., Hiner, Bradley C., Jankovic, Joseph, Allen, Jr., Fred H., Goetz, Christopher G., Mastaglia, Frank, Stajich, Jeffrey M., Gibson, Rachel A., Middleton, Lefkos T., Saunders, Ann M., Scott, Burton L., Small, Gary W., Nicodemus, Kristin K., Reed, Allison D., Schmechel, Donald E., Welsh-Bohmer, Kathleen A., Conneally, P. Michael, Roses, Allen D., Gilbert, John R., Vance, Jeffery M., Haines, Jonathan L., Pericak-Vance, Margaret A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society of Human Genetics 2002
Soggetti:
Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC379130/
https://ncbi.nlm.nih.gov/pubmed/11875758
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi