Mitochondrial Polymorphisms Significantly Reduce the Risk of Parkinson Disease

Mitochondrial (mt) impairment, particularly within complex I of the electron transport system, has been implicated in the pathogenesis of Parkinson disease (PD). More than half of mitochondrially encoded polypeptides form part of the reduced nicotinamide adenine dinucleotide dehydrogenase (NADH) com...

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Hlavní autoři: van der Walt, Joelle M., Nicodemus, Kristin K., Martin, Eden R., Scott, William K., Nance, Martha A., Watts, Ray L., Hubble, Jean P., Haines, Jonathan L., Koller, William C., Lyons, Kelly, Pahwa, Rajesh, Stern, Matthew B., Colcher, Amy, Hiner, Bradley C., Jankovic, Joseph, Ondo, William G., Allen Jr., Fred H., Goetz, Christopher G., Small, Gary W., Mastaglia, Frank, Stajich, Jeffrey M., McLaurin, Adam C., Middleton, Lefkos T., Scott, Burton L., Schmechel, Donald E., Pericak-Vance, Margaret A., Vance, Jeffery M.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society of Human Genetics 2003
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180345/
https://ncbi.nlm.nih.gov/pubmed/12618962
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