HER-2 gene amplification in human breast cancer without concurrent HER-2 over-expression

BACKGROUND: Testing for human epidermal growth factor receptor-2 (HER-2) in breast cancer is performed by either immunohistochemistry (IHC) or in situ hybridization (ISH). The growth factor receptor-bound protein-7 (GRB7) gene is in close proximity to HER-2 on chromosome 17q11-12 and codes a signal...

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Detalhes bibliográficos
Main Authors: Luoh, Shiuh-Wen, Ramsey, Betsy, Hanlon Newell, Amy, Troxell, Megan, Hu, Zhi, Chin, Koei, Spellman, Paul, Olson, Susan, Keenan, Edward
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2013
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791222/
https://ncbi.nlm.nih.gov/pubmed/24102037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2193-1801-2-386
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