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Neurexin and Neuroligin Mediate Retrograde Synaptic Inhibition in C. elegans

The synaptic adhesion molecules Neurexin and Neuroligin alter the development and function of synapses and are linked to autism in humans. We find that C. elegans Neurexin (NRX-1) and Neuroligin (NLG-1) mediate a retrograde synaptic signal that inhibits neurotransmitter release at neuromuscular junc...

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Sonraí Bibleagrafaíochta
Main Authors: Hu, Zhitao, Hom, Sabrina, Kudze, Tambudzai, Tong, Xia-Jing, Choi, Seungwon, Aramuni, Gayane, Zhang, Weiqi, Kaplan, Joshua M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791080/
https://ncbi.nlm.nih.gov/pubmed/22859820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1224896
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