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Assembling Single-Cell Genomes and Mini-Metagenomes From Chimeric MDA Products
Recent advances in single-cell genomics provide an alternative to largely gene-centric metagenomics studies, enabling whole-genome sequencing of uncultivated bacteria. However, single-cell assembly projects are challenging due to (i) the highly nonuniform read coverage and (ii) a greatly elevated nu...
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| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Mary Ann Liebert, Inc.
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3791033/ https://ncbi.nlm.nih.gov/pubmed/24093227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2013.0084 |
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