Metabolic Gene Remodeling and Mitochondrial Dysfunction in Failing Right Ventricular Hypertrophy due to Pulmonary Arterial Hypertension

BACKGROUND: Right ventricular dysfunction (RVD) is the most frequent cause of death in patients with pulmonary arterial hypertension. Whereas abnormal energy substrate utilization has been implicated in the development of chronic left heart failure, data describing such metabolic remodeling in RVD r...

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Autores principales: Gomez-Arroyo, Jose, Mizuno, Shiro, Szczepanek, Karol, Van Tassell, Benjamin, Natarajan, Ramesh, dos Remedios, Cristobal G., Drake, Jennifer I., Farkas, Laszlo, Kraskauskas, Donatas, Wijesinghe, Dayanjan S., Chalfant, Charles E., Bigbee, John, Abbate, Antonio, Lesnefsky, Edward J., Bogaard, Harm J., Voelkel, Norbert F.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790960/
https://ncbi.nlm.nih.gov/pubmed/23152488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.111.966127
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