Increased Eicosanoid Levels in the Sugen/Chronic Hypoxia Model of Severe Pulmonary Hypertension

Inflammation and altered immunity are recognized components of severe pulmonary arterial hypertension in human patients and in animal models of PAH. While eicosanoid metabolites of cyclooxygenase and lipoxygenase pathways have been identified in the lungs from pulmonary hypertensive animals their ro...

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Udgivet i:PLoS One
Main Authors: Al-Husseini, Aysar, Wijesinghe, Dayanjan S., Farkas, Laszlo, Kraskauskas, Donatas, Drake, Jennifer I., Van Tassel, Ben, Abbate, Antonio, Chalfant, Charles E., Voelkel, Norbert F.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364907/
https://ncbi.nlm.nih.gov/pubmed/25785937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120157
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