Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature

We have recently identified T cells as important mediators of ischemic brain damage, but the contribution of the different T-cell subsets is unclear. Forkhead box P3 (FoxP3)–positive regulatory T cells (Tregs) are generally regarded as prototypic anti-inflammatory cells that maintain immune toleranc...

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Detaylı Bibliyografya
Asıl Yazarlar: Kleinschnitz, Christoph, Kraft, Peter, Dreykluft, Angela, Hagedorn, Ina, Göbel, Kerstin, Schuhmann, Michael K., Langhauser, Friederike, Helluy, Xavier, Schwarz, Tobias, Bittner, Stefan, Mayer, Christian T., Brede, Marc, Varallyay, Csanad, Pham, Mirko, Bendszus, Martin, Jakob, Peter, Magnus, Tim, Meuth, Sven G., Iwakura, Yoichiro, Zernecke, Alma, Sparwasser, Tim, Nieswandt, Bernhard, Stoll, Guido, Wiendl, Heinz
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2013
Konular:
Thrombosis and Hemostasis
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790947/
https://ncbi.nlm.nih.gov/pubmed/23160472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-04-426734
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