Sustained Reperfusion after Blockade of Glycoprotein-Receptor-Ib in Focal Cerebral Ischemia: An MRI Study at 17.6 Tesla

BACKGROUND: Inhibition of early platelet adhesion by blockade of glycoprotein-IB (GPIb) protects mice from ischemic stroke. To elucidate underlying mechanisms in-vivo, infarct development was followed by ultra-high field MRI at 17.6 Tesla. METHODS: Cerebral infarction was induced by transient-middle...

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Detalhes bibliográficos
Main Authors: Pham, Mirko, Helluy, Xavier, Kleinschnitz, Christoph, Kraft, Peter, Bartsch, Andreas J., Jakob, Peter, Nieswandt, Bernhard, Bendszus, Martin, Stoll, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069968/
https://ncbi.nlm.nih.gov/pubmed/21483769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018386
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