The Nociceptin/Orphanin FQ System Is Modulated in Patients Admitted to ICU with Sepsis and after Cardiopulmonary Bypass

BACKGROUND AND OBJECTIVES: Nociceptin/Orphanin FQ (N/OFQ) is a non-classical endogenous opioid peptide that modulates immune function in vitro. Its importance in inflammation and human sepsis is unknown. The objectives of this study were to determine the relationship between N/OFQ, transcripts for i...

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Main Authors: Thompson, Jonathan P., Serrano-Gomez, Alcira, McDonald, John, Ladak, Nadia, Bowrey, Sarah, Lambert, David G.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790749/
https://ncbi.nlm.nih.gov/pubmed/24124588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076682
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