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Mouse extraembryonic arterial vessels harbor precursors capable of maturing into definitive HSCs
During mouse development, definitive hematopoietic stem cells (dHSCs) emerge by late E10.5 to E11 in several hematopoietic sites. Of them, the aorta-gonad-mesonephros (AGM) region drew particular attention owing to its capacity to autonomously initiate and expand dHSCs in culture, indicating its key...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Hematology
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3790504/ https://ncbi.nlm.nih.gov/pubmed/23863896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-12-470971 |
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