Human SNP Links Differential Outcomes in Inflammatory and Infectious Disease to a FOXO3-Regulated Pathway

The clinical course and eventual outcome, or prognosis, of complex diseases varies enormously between affected individuals. This variability critically determines the impact a disease has on a patient’s life but is very poorly understood. Here, we exploit existing genome-wide association study data...

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Hauptverfasser: Lee, James C., Espéli, Marion, Anderson, Carl A., Linterman, Michelle A., Pocock, Joanna M., Williams, Naomi J., Roberts, Rebecca, Viatte, Sebastien, Fu, Bo, Peshu, Norbert, Hien, Tran Tinh, Phu, Nguyen Hoan, Wesley, Emma, Edwards, Cathryn, Ahmad, Tariq, Mansfield, John C., Gearry, Richard, Dunstan, Sarah, Williams, Thomas N., Barton, Anne, Vinuesa, Carola G., Parkes, Miles, Lyons, Paul A., Smith, Kenneth G.C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cell Press 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790457/
https://ncbi.nlm.nih.gov/pubmed/24035192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.08.034
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