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Synergistic Effects of Mutations in Cytochrome P450cam Designed to Mimic CYP101D1

A close ortholog to the cytochrome P450cam (CYP101A1) that catalyzes the same hydroxylation of camphor to 5-exo hydroxycamphor is CYP101D1. There are potentially important differences in and around the active site that could contribute to subtle functional differences. Adjacent to the heme iron liga...

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Hlavní autoři: Batabyal, Dipanwita, Li, Huiying, Poulos, Thomas L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790332/
https://ncbi.nlm.nih.gov/pubmed/23865948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400676d
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