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Synergistic Effects of Mutations in Cytochrome P450cam Designed to Mimic CYP101D1
A close ortholog to the cytochrome P450cam (CYP101A1) that catalyzes the same hydroxylation of camphor to 5-exo hydroxycamphor is CYP101D1. There are potentially important differences in and around the active site that could contribute to subtle functional differences. Adjacent to the heme iron liga...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3790332/ https://ncbi.nlm.nih.gov/pubmed/23865948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400676d |
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