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Aurora A kinase and its substrate TACC3 are required for central spindle assembly

Cell division entails a marked reorganization of the microtubule network to form the spindle, a molecular machine that ensures accurate chromosome segregation to the daughter cells. Spindle organization is highly dynamic throughout mitosis and requires the activity of several kinases and complex reg...

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Autori principali: Lioutas, Antonios, Vernos, Isabelle
Natura: Artigo
Lingua:Inglês
Pubblicazione: European Molecular Biology Organization 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790052/
https://ncbi.nlm.nih.gov/pubmed/23887685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2013.109
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