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Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis

Centrosomes act as sites of microtubule growth, but little is known about how the number and stability of microtubules emanating from a centrosome are controlled during the cell cycle. We studied the role of the TACC3–XMAP215 complex in this process by using purified proteins and Xenopus laevis egg...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kinoshita, Kazuhisa, Noetzel, Tim L., Pelletier, Laurence, Mechtler, Karl, Drechsel, David N., Schwager, Anne, Lee, Mike, Raff, Jordan W., Hyman, Anthony A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171544/
https://ncbi.nlm.nih.gov/pubmed/16172205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200503023
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