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Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules

Disruption of the function of the A-type Aurora kinase of Drosophila by mutation or RNAi leads to a reduction in the length of astral microtubules in syncytial embryos, larval neuroblasts, and cultured S2 cells. In neuroblasts, it can also lead to loss of an organized centrosome and its associated a...

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Autores principales: Giet, Régis, McLean, Doris, Descamps, Simon, Lee, Michael J., Raff, Jordan W., Prigent, Claude, Glover, David M.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173350/
https://ncbi.nlm.nih.gov/pubmed/11827981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200108135
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