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Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules

Disruption of the function of the A-type Aurora kinase of Drosophila by mutation or RNAi leads to a reduction in the length of astral microtubules in syncytial embryos, larval neuroblasts, and cultured S2 cells. In neuroblasts, it can also lead to loss of an organized centrosome and its associated a...

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Detalhes bibliográficos
Main Authors: Giet, Régis, McLean, Doris, Descamps, Simon, Lee, Michael J., Raff, Jordan W., Prigent, Claude, Glover, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173350/
https://ncbi.nlm.nih.gov/pubmed/11827981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200108135
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