Regulation of Mammalian Target of Rapamycin Complex 1 by Bcl-2 and Bcl-X(L) Proteins

Mammalian target of rapamycin complex 1 (mTORC1) is a key regulator of cell growth and metabolism. Its activity is controlled by various types of signals, including growth factors, nutrients, and stresses. In this study, we show that changes in expression levels of two antiapoptotic proteins, Bcl-2...

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Detalhes bibliográficos
Main Authors: Zou, Huafei, Lai, Yumei, Zhao, Xuwen, Yan, Gonghong, Ma, Dongzhu, Cardenes, Nayra, Shiva, Sruti, Liu, Yongjian, Bai, Xiaochun, Jiang, Yong, Jiang, Yu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789978/
https://ncbi.nlm.nih.gov/pubmed/23960074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.505370
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