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Regulation of Karyopherin α1 and Nuclear Import by Mammalian Target of Rapamycin

Under conditions of reduced mitogen or nutritional substrate levels, the serine/threonine kinase target of rapamycin can augment the nuclear content of distinct transcription factors and promote the induction of stress response genes. In its latent (i.e., unphosphorylated) form, the transcription fa...

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Autori principali: Fielhaber, Jill A., Tan, Jason, Joung, Kwang-Bo, Attias, Ortal, Huegel, Stefanie, Bader, Michael, Roux, Philippe P., Kristof, Arnold S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340278/
https://ncbi.nlm.nih.gov/pubmed/22399302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.246785
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