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The Switch I Region of Rheb Is Critical for Its Interaction with FKBP38
The Ras-like small GTPase Rheb is an upstream activator of the mammalian target of rapamycin (mTOR). It has recently been shown that Rheb activates mTOR by binding to its endogenous inhibitor FKBP38 and preventing it from association with mTOR. The interaction of Rheb with FKBP38 is controlled by it...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2533802/ https://ncbi.nlm.nih.gov/pubmed/18658153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802356200 |
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