Angiopoietin-like Protein 4 Inhibition of Lipoprotein Lipase: EVIDENCE FOR REVERSIBLE COMPLEX FORMATION

Elevated triglycerides are associated with an increased risk of cardiovascular disease, and lipoprotein lipase (LPL) is the rate-limiting enzyme for the hydrolysis of triglycerides from circulating lipoproteins. The N-terminal domain of angiopoietin-like protein 4 (ANGPTL4) inhibits LPL activity. AN...

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Detalhes bibliográficos
Main Authors: Lafferty, Michael J., Bradford, Kira C., Erie, Dorothy A., Neher, Saskia B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Lipids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789953/
https://ncbi.nlm.nih.gov/pubmed/23960078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.497602
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