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Programmable DNA-binding Small Molecules
Aberrant gene expression is responsible for a myriad of human diseases from infectious diseases to cancer. Precise regulation of these genes via specific interactions with the DNA double helix could pave the way for novel therapeutics. Pyrrole-imidazole polyamides are small molecules capable of bind...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3789866/ https://ncbi.nlm.nih.gov/pubmed/23665141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.04.023 |
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