Sequestration by IFIT1 Impairs Translation of 2′O-unmethylated Capped RNA

Viruses that generate capped RNA lacking 2′O methylation on the first ribose are severely affected by the antiviral activity of Type I interferons. We used proteome-wide affinity purification coupled to mass spectrometry to identify human and mouse proteins specifically binding to capped RNA with di...

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Main Authors: Habjan, Matthias, Hubel, Philipp, Lacerda, Livia, Benda, Christian, Holze, Cathleen, Eberl, Christian H., Mann, Angelika, Kindler, Eveline, Gil-Cruz, Cristina, Ziebuhr, John, Thiel, Volker, Pichlmair, Andreas
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789756/
https://ncbi.nlm.nih.gov/pubmed/24098121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003663
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