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SARS-CoV and IFN: Too Little, Too Late

Dysregulated type I interferon (IFN-I) expression can lead to severe pathology and disease. In this issue of Cell Host & Microbe, Channappanavar et al. (2016) use a SARS-coronavirus animal model to describe how rapid and robust virus replication with delayed IFN-I can lead to lung immunopatholog...

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Bibliographic Details
Published in:Cell Host Microbe
Main Authors: Kindler, Eveline, Thiel, Volker
Format: Artigo
Language:Inglês
Published: Elsevier Inc. 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7104995/
https://ncbi.nlm.nih.gov/pubmed/26867172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2016.01.012
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