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A Talented Duo: IFIT1 and IFIT3 Patrol Viral RNA Caps

Hosts respond to viral infection by expressing interferon-stimulated genes, of which IFITs are potent inhibitors of viral RNA translation. Johnson et al. (2018) solved the structure of the IFIT1-IFIT3 complex bound cap 0 RNA and explored their concerted antiviral activity.

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Bibliografiske detaljer
Udgivet i:Immunity
Main Authors: Choi, Youn Jung, Bowman, James W., Jung, Jae U.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6906926/
https://ncbi.nlm.nih.gov/pubmed/29562196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.03.001
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