Double siRNA-targeting of cIAP2 and LIVIN results in synergetic sensitization of HCT-116 cells to oxaliplatin treatment

PURPOSE: Most colon cancers show low sensitivity to treatment with oxaliplatin and a specific strategy is needed to overcome this problem. Our approach uses RNA interference to silence the expression of target genes responsible for the development of oxaliplatin resistance. Profile analysis of genes...

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Autores principales: Bavykin, Andrey S, Korotaeva, Alexandra A, Poyarkov, Stanislav V, Syrtsev, Alexandr V, Tjulandin, Sergei A, Karpukhin, Alexandr V
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789649/
https://ncbi.nlm.nih.gov/pubmed/24098083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S44893
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