MLML: consistent simultaneous estimates of DNA methylation and hydroxymethylation

Motivation: The two major epigenetic modifications of cytosines, 5-methylcytosine (5-mC) and 5-hydroxymethylcytosine (5-hmC), coexist with each other in a range of mammalian cell populations. Increasing evidence points to important roles of 5-hmC in demethylation of 5-mC and epigenomic regulation in...

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Main Authors: Qu, Jianghan, Zhou, Meng, Song, Qiang, Hong, Elizabeth E., Smith, Andrew D.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2013
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Applications Notes
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789553/
https://ncbi.nlm.nih.gov/pubmed/23969133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt459
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