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Formation of S-Cl phosphorothioate adduct radicals in dsDNA-S-oligomers: Hole transfer to guanine vs. disulfide anion radical formation

In phosphorothioate containing dsDNA-oligomers (S-oligomers), one of the two non-bridging oxygen atoms in the phosphate moiety of sugar-phosphate backbone is replaced by sulphur. In this work, electron spin resonance (ESR) studies of one-electron oxidation of several S-oligos by Cl(2)•(−) at low tem...

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Autori principali: Adhikary, Amitava, Kumar, Anil, Palmer, Brian J., Todd, Andrew D., Sevilla, Michael D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789529/
https://ncbi.nlm.nih.gov/pubmed/23885974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja406121x
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