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Identifying Yersinia YopH-targeted signal transduction pathways that impair neutrophil responses during in vivo murine infection

Identifying molecular targets of Yersinia virulence effectors, or Yops, during animal infection is challenging because few cells are targeted by Yops in an infected organ and isolating these sparse effector-containing cells is difficult. YopH, a tyrosine phosphatase, is essential for full virulence...

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Hlavní autoři: Rolán, Hortensia G., Durand, Enrique A., Mecsas, Joan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789382/
https://ncbi.nlm.nih.gov/pubmed/24034616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2013.08.013
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