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Identifying Yersinia YopH-targeted signal transduction pathways that impair neutrophil responses during in vivo murine infection

Identifying molecular targets of Yersinia virulence effectors, or Yops, during animal infection is challenging because few cells are targeted by Yops in an infected organ and isolating these sparse effector-containing cells is difficult. YopH, a tyrosine phosphatase, is essential for full virulence...

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Detalhes bibliográficos
Main Authors: Rolán, Hortensia G., Durand, Enrique A., Mecsas, Joan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789382/
https://ncbi.nlm.nih.gov/pubmed/24034616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2013.08.013
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