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Cytochrome P450s in the Regulation of Cellular Retinoic Acid Metabolism

The active metabolite of vitamin A, retinoic acid (RA), is a powerful regulator of gene transcription. RA is also a therapeutic drug. The oxidative metabolism of RA by certain members of the cytochrome P450 (CYP) superfamily helps to maintain tissue RA concentrations within appropriate bounds. The C...

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Bibliographic Details
Main Authors: Ross, A. Catharine, Zolfaghari, Reza
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789243/
https://ncbi.nlm.nih.gov/pubmed/21529158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-nutr-072610-145127
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