A new platinum(II) compound anticancer drug candidate with selective cytotoxicity for breast cancer cells

[Pt(O,O′-acac)(γ-acac)(DMS)] (PtAcD) is able to induce apoptosis in various human cancer cells, including the cisplatin-resistant human breast carcinoma MCF-7 cells. Here, to confirm that PtAcD has the potentiality for therapeutic intervention, we studied its effects in primary cultured epithelial b...

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Bibliografiske detaljer
Main Authors: Muscella, A, Vetrugno, C, Fanizzi, F P, Manca, C, De Pascali, S A, Marsigliante, S
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789173/
https://ncbi.nlm.nih.gov/pubmed/24030148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.315
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